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Details for Patent: 5,260,291

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Summary for Patent: 5,260,291

Title: Tetrazine derivatives
Abstract:[ 3H]-Imidazo[ 5,1-d] -1,2,3,5-tetrazin-4-one derivatives of the formula: ##STR1## wherein R.sup.1 represents hydrogen, or an alkyl, alkenyl or alkynyl group containing up to 6 carbon atoms, each such group being unsubstituted or substituted by from one to three substituents selected from halogen atoms, alkoxy, alkylthio, alkylsulphinyl and alkylsulphonyl groups containing up to 4 carbon atoms, and optionally substituted phenyl groups, or R.sup.1 represents a cycloalkyl group containing from 3 to 8 carbon atoms, and R.sup.2 represents a carbamoyl group optionally N-substituted by one or two groups selected ftom alkyl and alkenyl groups containing up to 4 carbon atoms, and cycloalkyl groups containing 3 to 8 carbon atoms, are new therapeutically useful compounds possessing antineoplastic and immunomodulatory activity.
Inventor(s): Lunt; Edward (Norfolk, GB2), Stevens; Malcolm F. G. (Birmingham, GB2), Stone; Robert (Montrose, AU), Wooldridge; Kenneth R. H. (Lincolnshire, GB2), Newlands; Edward S. (London, GB2)
Assignee: Cancer Research Campaign Technology Limited (London, GB2)
Application Number:07/781,020
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent PDF download available with subscription

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Foreign Priority and PCT Information for Patent: 5,260,291

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8125791Aug 24, 1981

International Patent Family for Patent: 5,260,291

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
Sweden8204817Aug 23, 1982
Italy1152505Jan 07, 1987
Malaysia116474Feb 28, 2004
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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