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Details for Patent: 5,246,925

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Summary for Patent: 5,246,925

Title: 19-nor-vitamin D compounds for use in treating hyperparathyroidism
Abstract:This invention provides a novel class of vitamin D-related compounds, namely the 1.alpha.-hydroxy-19-nor-vitamin D analogs, as well as a general method for their chemical synthesis. The compounds exhibit pronounced activity in arresting the proliferation of undifferentiated cells, including malignant cells, and in inducing their differentiation, and thus represent novel therapeutic agents for the treatment of malignant and other diseases characterized by the proliferative growth of undifferentiated cells. Formulations for therapeutic use and treatment methods are also provided.
Inventor(s): DeLuca; Hector F. (Deerfield, WI), Schnoes; Heinrich K. (Madison, WI), Perlman; Kato L. (Madison, WI), Sicinski; Rafal R. (Warsaw, PL), Prahl; Jean M. (Madison, WI)
Assignee: Wisconsin Alumni Research Foundation (Madison, WI)
Application Number:07/960,241
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent PDF download available with subscription

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International Patent Family for Patent: 5,246,925

Country Document Number Publication Date
South Africa9007119Oct 30, 1991
World Intellectual Property Organization (WIPO)9010620Sep 20, 1990
United States of America5237110Aug 17, 1993
United States of America5321018Jun 14, 1994
United States of America5342975Aug 30, 1994
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