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Details for Patent: 5,246,925

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Summary for Patent: 5,246,925

Title: 19-nor-vitamin D compounds for use in treating hyperparathyroidism
Abstract:This invention provides a novel class of vitamin D-related compounds, namely the 1.alpha.-hydroxy-19-nor-vitamin D analogs, as well as a general method for their chemical synthesis. The compounds exhibit pronounced activity in arresting the proliferation of undifferentiated cells, including malignant cells, and in inducing their differentiation, and thus represent novel therapeutic agents for the treatment of malignant and other diseases characterized by the proliferative growth of undifferentiated cells. Formulations for therapeutic use and treatment methods are also provided.
Inventor(s): DeLuca; Hector F. (Deerfield, WI), Schnoes; Heinrich K. (Madison, WI), Perlman; Kato L. (Madison, WI), Sicinski; Rafal R. (Warsaw, PL), Prahl; Jean M. (Madison, WI)
Assignee: Wisconsin Alumni Research Foundation (Madison, WI)
Application Number:07/960,241
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent PDF download available with subscription

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International Patent Family for Patent: 5,246,925

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
Israel93455Dec 29, 1994
Germany69006052May 05, 1994
Australia5198890Oct 09, 1990
Germany69006052Mar 03, 1994
Argentina246254Jul 29, 1994
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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