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|Title:||Method for dissolving arginineamides and pharmaceutical compositions containing them|
|Abstract:||A method for dissolving an arginineamide of the invention comprising dissolving N.sup.2 -arylsulfonyl-L-arginineamide having the general formula (I) ##STR1## wherein R.sup.1 represents a (2R, 4R)-4-alkyl-2-carboxypiperizino group and R.sup.2 represents a phenyl group or a condensed polycyclic compound residue which may be substituted with one or more substituents selected from lower alkyl groups, lower alkoxy groups and lower alkyl-substituted amino groups, said condensed polycyclic compound residue including a benzene ring which binds to sulfur atom of the sulfonyl group in the general formula (I) and is condensed with one or more other rings which may be heterocyclic and having 7 to 14 carbon atoms as the ring-constituent atoms; and/or its salt in a solvent of alcohol and water is disclosed herein. And, the pharmaceutical composition comprising N.sup.2 -arylsulfonyl-L-arginineamide having the general formula (I), an alcohol and water is disclosed herein.|
|Inventor(s):||Ofuchi; Kunihiko (Hasaki, JP), Nomura; Tatsuo (Hasaki, JP)|
|Assignee:||Mitsubishi Kasei Corporation (Tokyo, JP)|
Patent Claim Types:|
see list of patent claims
|Use; Compound; Composition;|
|Foriegn Application Priority Data|
|Foreign Country||Foreign Patent Number||Foreign Patent Date|
|Japan||62-188484||Jul 28, 1987|
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Japan||H0576929||Oct 25, 1993|
|Germany||122005000056||Feb 23, 2006|
|Japan||S6431727||Feb 02, 1989|
|Germany||3866303||Jan 02, 1992|
|European Patent Office||0301970||Feb 01, 1989|
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