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Details for Patent: 5,214,052

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Summary for Patent: 5,214,052

Title: Method for dissolving arginineamides and pharmaceutical compositions containing them
Abstract:A method for dissolving an arginineamide of the invention comprising dissolving N.sup.2 -arylsulfonyl-L-arginineamide having the general formula (I) ##STR1## wherein R.sup.1 represents a (2R, 4R)-4-alkyl-2-carboxypiperizino group and R.sup.2 represents a phenyl group or a condensed polycyclic compound residue which may be substituted with one or more substituents selected from lower alkyl groups, lower alkoxy groups and lower alkyl-substituted amino groups, said condensed polycyclic compound residue including a benzene ring which binds to sulfur atom of the sulfonyl group in the general formula (I) and is condensed with one or more other rings which may be heterocyclic and having 7 to 14 carbon atoms as the ring-constituent atoms; and/or its salt in a solvent of alcohol and water is disclosed herein. And, the pharmaceutical composition comprising N.sup.2 -arylsulfonyl-L-arginineamide having the general formula (I), an alcohol and water is disclosed herein.
Inventor(s): Ofuchi; Kunihiko (Hasaki, JP), Nomura; Tatsuo (Hasaki, JP)
Assignee: Mitsubishi Kasei Corporation (Tokyo, JP)
Application Number:07/851,248
Patent Claim Types:
see list of patent claims
Use; Compound; Composition;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Pfizer
ACOVA
argatroban
INJECTABLE;INJECTION020883Jun 30, 2000RXYes5,214,052<disabled>
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Foreign Priority and PCT Information for Patent: 5,214,052

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan62-188484Jul 28, 1987

International Patent Family for Patent: 5,214,052

Country Document Number Publication Date
JapanH0576929Oct 25, 1993
JapanS6431727Feb 02, 1989
European Patent Office (EPO)0301970Feb 01, 1989
Germany122005000056Feb 23, 2006
Germany3866303Jan 02, 1992
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