|Title:||1H-imidazole derivative compounds and pharmaceutical compositions containing the same|
|Abstract:||The 1H-imidazole derivative compound of formula I: ##STR1## and its nontoxic addition salts, particularly the nitrate addition salt, are more effective as antimycotic agents and are unexpectedly safer than the corresponding prior art compounds, especially the compound in which the sulfur atom of the benzothiophene ring of the above compound is replaced by an oxygen atom. Pharmaceutical compositions containing an effective amount of the compound of formula I, e.g. 1 to 5% by weight, in a pharmaceutical carrier are safer, more effective, and, in some cases, more reliable with fewer side effects than currently used antimycotic preparations.|
|Inventor(s):||Foguet; Rafael (Barcelona, ES), Moreno; Marcial (Barcelona, ES), Raga; Manuel (Barcelona, ES), Cuberes; Rosa M. (Barcelona, ES), Castello; Jose M. (Barcelona, ES), Ortiz; Jose A. (Barcelona, ES)|
|Assignee:||Ferrer Internacional S.A. (Barcelona, ES)|
Patent Claim Types:|
see list of patent claims
|Compound; Use; Composition;|
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Spain||535656||Feb 16, 1986|
|European Patent Office||0151477||Sep 12, 1990|
|Canada||1250586||Feb 28, 1989|
|South Africa||8410086||Apr 30, 1986|
|Philippines||21405||Oct 15, 1987|
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