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Details for Patent: 5,100,899

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Summary for Patent: 5,100,899

Title: Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
Abstract:This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
Inventor(s): Calne; Roy (Cambridge, GB2)
Assignee:
Application Number:07/362,354
Patent Claim Types:
see list of patent claims
Use; Delivery;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Pf Prism Cv
RAPAMUNE
sirolimus
SOLUTION;ORAL021083Sep 15, 1999RXYes5,100,899*PED<disabled>Y
Pf Prism Cv
RAPAMUNE
sirolimus
TABLET;ORAL021110Jan 25, 2010RXNo5,100,899*PED<disabled>Y
Pf Prism Cv
RAPAMUNE
sirolimus
TABLET;ORAL021110Aug 25, 2000RXNo5,100,899*PED<disabled>Y
Pf Prism Cv
RAPAMUNE
sirolimus
TABLET;ORAL021110Aug 22, 2002RXYes5,100,899*PED<disabled>Y
Pf Prism Cv
RAPAMUNE
sirolimus
TABLET;ORAL021110Feb 23, 2004DISCNNo5,100,899*PED<disabled>Y
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International Patent Family for Patent: 5,100,899

Country Document Number Publication Date
United States5212155May 18, 1993
United States5308847May 03, 1994
United States5403833Apr 04, 1995
United States5461058Oct 24, 1995
Singapore44632Dec 19, 1997
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