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Details for Patent: 5,100,899

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Summary for Patent: 5,100,899

Title: Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
Abstract:This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
Inventor(s): Calne; Roy (Cambridge, GB2)
Assignee:
Application Number:07/362,354
Patent Claim Types:
see list of patent claims
Use; Delivery;
Patent PDF download available with subscription

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International Patent Family for Patent: 5,100,899

Country Document Number Publication Date Supplementary Protection Certificate SPC Country SPC Expiration
JapanH0373158Mar 28, 1991
Germany10199045Jul 13, 2006
Australia638253Jun 24, 1993
Austria135215Mar 15, 1996
Hungary206974Mar 01, 1993
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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