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|Title:||Soft steroids having anti-inflammatory activity|
|Abstract:||The invention provides novel soft steroidal anti-inflammatory agents, pharmaceutical compositions containing said agents, and methods of administering same to mammals in the treatment of inflammation. Preferred compounds of the invention include haloalkyl 17.alpha.-alkoxycarbonyloxy-11.beta.-hydroxyandrost-4-en-3-one-17.beta.-ca rboxylates and the corresponding .DELTA..sup.1,4 compounds, optionally bearing 6.alpha.- and/or 9.alpha.-fluorine and 16.alpha.- or 16.beta.-methyl substituents. Especially preferred compounds include haloalkyl 17.alpha.-alkoxycarbonyloxy-9.alpha.-fluoro-11.beta.-hydroxy-16-methylandr osta-1,4-dien-3-one-17.beta.-carboxylates.|
|Inventor(s):||Bodor; Nicholas S. (Gainesville, FL)|
|Assignee:||Bodor; Nicholas S. (Gainesville, FL)|
Patent Claim Types:|
see list of patent claims
|Compound; Composition; Use;|
|Country||Document Number||Publication Date||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|France||2486529||Jan 15, 1982|
|Spain||8300785||Feb 01, 1983|
|Australia||7259181||Jan 14, 1982|
|Austria||379816||Mar 10, 1986|
|Portugal||73348||Sep 23, 1982|
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