Details for Patent: 8,420,676
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Which drugs does patent 8,420,676 protect, and when does it expire?
Patent 8,420,676 protects SIVEXTRO and is included in two NDAs.
This patent has thirty-seven patent family members in twenty-three countries.
Summary for Patent: 8,420,676
| Title: | Oxazolidinone derivatives |
| Abstract: | The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone derivatives of the present invention show inhibitory activity against a broad spectrum of bacteria and lower toxicity. The prodrugs, prepared by reacting the compound having hydroxyl group with amino acid or phosphate, have an excellent efficiency on solubility thereof against water. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as, Staphylococci, Enterococci and Streptococci anaerobic microorganisms such as Bacteroides and Clostridia, and acid-resistant microorganisms such as Mycobacterium tuberculosis and Mycobacterium avium. Accordingly, the compositions comprising the oxazolidinone are used in an antibiotic. |
| Inventor(s): | Rhee; Jae Keol (Kyonggido, KR), Im; Weon Bin (Yongin-si, KR), Cho; Chong Hwan (Yongin-si, KR), Choi; Sung Hak (Seongnam-si, KR), Lee; Tae Ho (Yongin-si, KR) |
| Assignee: | Dong-A Pharmaceuticals Co. Ltd. (Seoul, KR) |
| Application Number: | 12/211,655 |
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Patent Claim Types: see list of patent claims | Compound; Composition; Use; |
Drugs Protected by US Patent 8,420,676
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cubist Pharms Llc | SIVEXTRO | tedizolid phosphate | POWDER;INTRAVENOUS | 205436-001 | Jun 20, 2014 | RX | Yes | Yes | ⤷ Try a Trial | ⤷ Try a Trial | Y | Y | METHOD OF TREATING BACTERIAL INFECTIONS | ⤷ Try a Trial | ||
| Cubist Pharms Llc | SIVEXTRO | tedizolid phosphate | TABLET;ORAL | 205435-001 | Jun 20, 2014 | RX | Yes | Yes | ⤷ Try a Trial | ⤷ Try a Trial | Y | Y | METHOD OF TREATING BACTERIAL INFECTIONS | ⤷ Try a Trial | ||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 8,420,676
| Foriegn Application Priority Data | ||
| Foreign Country | Foreign Patent Number | Foreign Patent Date |
| South Korea | 10-2003-0093342 | Dec 18, 2003 |
| South Korea | 10-2004-0058809 | Jul 27, 2004 |
International Family Members for US Patent 8,420,676
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Austria | 514686 | ⤷ Try a Trial | |||
| Australia | 2004299413 | ⤷ Try a Trial | |||
| Australia | 2009200606 | ⤷ Try a Trial | |||
| Brazil | PI0417800 | ⤷ Try a Trial | |||
| Canada | 2549062 | ⤷ Try a Trial | |||
| China | 101982468 | ⤷ Try a Trial | |||
| China | 102516238 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
