Details for Patent: 6,362,178
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Summary for Patent: 6,362,178
| Title: | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
| Abstract: | The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction. |
| Inventor(s): | Niewohner; Ulrich (Wermelskirchen, DE), Es-Sayed; Mazen (Langenfeld, DE), Haning; Helmut (Wuppertal, DE), Schenke; Thomas (Gladbach, DE), Schlemmer; Karl-Heinz (Wuppertal, DE), Keldenich; Jorg (Wuppertal, DE), Bischoff; Erwin (Wuppertal, DE), Perzborn; Elisabeth (Wuppertal, DE), Dembowsky; Klaus (Boston, MA), Serno; Peter (Gladbach, DE), Nowakowski; Marc (Wuppertal, DE) |
| Assignee: | Bayer Aktiengesellschaft (Leverkusen, DE) |
| Application Number: | 09/554,162 |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 6,362,178 |
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Patent Claim Types: see list of patent claims | Compound; Use; |
Drugs Protected by US Patent 6,362,178
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 6,362,178
| Foriegn Application Priority Data | ||
| Foreign Country | Foreign Patent Number | Foreign Patent Date |
| Germany | 197 50 085 | Nov 12, 1997 |
| Germany | 198 12 462 | Mar 23, 1998 |
| Germany | 198 40 289 | Sep 04, 1998 |
| PCT Information | |||
| PCT Filed | October 31, 1998 | PCT Application Number: | PCT/EP98/06910 |
| PCT Publication Date: | May 20, 1999 | PCT Publication Number: | WO99/24433 |
International Family Members for US Patent 6,362,178
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Argentina | 013759 | ⤷ Try a Trial | |||
| Argentina | 035972 | ⤷ Try a Trial | |||
| Austria | 213246 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
