Details for Patent: 6,232,304
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Summary for Patent: 6,232,304
Title: | Inclusion complexes of aryl-heterocyclic salts |
Abstract: | Compositions of matter comprising a pharmaceutically acceptable salt of an aryl-heterocyclic compound, such as ziprasidone, in a cyclodextrin. Preferred cyclodextrins are SBECD and HPBCD. The composition can comprise a dry mixture, a dry inclusion complex or an aqueous solution. The salt/cyclodextrin inclusion complex preferably provides an amount of ziprasidone of at least 2.5 mgA/ml when the complex is dissolved in water at 40% w/v. A variety of ziprasidone salts are preferred, including the mesylate, esylate, besylate, tartrate, napsylate, and tosylate. |
Inventor(s): | Kim; Yesook (Branford, CT), Johnson; Kevin C. (Niantic, CT), Shanker; Ravi M. (Groton, CT) |
Assignee: | Pfizer Inc. (New York, NY) |
Application Number: | 09/147,239 |
Patent Claim Types: see list of patent claims | Composition; Compound; Formulation; |
Drugs Protected by US Patent 6,232,304
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Foreign Priority and PCT Information for Patent: 6,232,304
PCT Information | |||
PCT Filed | April 01, 1997 | PCT Application Number: | PCT/IB97/00321 |
PCT Publication Date: | November 13, 1997 | PCT Publication Number: | WO97/41896 |
International Family Members for US Patent 6,232,304
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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African Regional IP Organization (ARIPO) | 796 | ⤷ Try a Trial | |||
African Regional IP Organization (ARIPO) | 9700977 | ⤷ Try a Trial | |||
Argentina | 007002 | ⤷ Try a Trial | |||
Argentina | 045528 | ⤷ Try a Trial | |||
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