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Last Updated: March 28, 2024

Details for Patent: 5,053,432


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Summary for Patent: 5,053,432
Title: Naphthoquinone derivatives
Abstract:Novel antiprotozoal naphthoquinones having the general formula ##STR1## (wherein either R.sup.1 is hydrogen and R.sup.2 is selected from C.sub.1-6 alkoxy, aralkoxy, C.sub.1-6 alkyl-C.sub.1-6 alkoxy, phenyl substituted by one or two groups selected from halogen and C.sub.1-6 alkyl, halogen and perhalo-C.sub.1-6 alkyl; or R.sup.1 and R.sup.2 are both C.sub.1-6 alkyl or phenyl; and n is 0 or 1) and salt thereof. The compounds of formula (I) are useful for the treatment or prophylaxis of protozoal diseases including malaria, theileriosis and coccidiosis. Various processes for preparing compounds of formula (I) are described.
Inventor(s): Hudson; Alan T. (Sevenoaks, GB), Randall; Anthony W. (Hayes, GB)
Assignee: Burroughs Wellcome Co. (Research Triangle Park, NC)
Application Number:07/456,052
Patent Claim Types:
see list of patent claims
Compound; Use; Dosage form; Composition;

Drugs Protected by US Patent 5,053,432

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 5,053,432

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom8310141Apr 14, 1983

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