Details for Patent: 4,880,631
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Summary for Patent: 4,880,631
| Title: | Controlled porosity osmotic pump |
| Abstract: | The instant invention is directed to an osmotic pump, for the controlled release of diltiazem L-malate to an environment of use, said pump comprising: (A) a core which comprises a therapeutically effective amount of diltiazem L-malate and an effective buffering amount of sodium bitartrate surrounded by (B) a rate controlling water insoluble wall, having a fluid permeability of 6.96.times.10.sup.-18 to 6.96.times.10.sup.-14 cm.sup.3 sec/g and a reflection coefficient of less than 0.5, prepared from: (i) a polymer permeable to water but impermeable to solute and (ii) 0.1 to 60% by weight, based on the total weight of (i) and (ii), of at least one pH insensitive pore forming additive dispersed throughout said wall. |
| Inventor(s): | Haslam; John L. (Lawrence, KS), Rork; Gerald S. (Lawrence, KS) |
| Assignee: | Merck & Co., Inc. (Rahway, NJ) |
| Application Number: | 07/100,665 |
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Patent Claim Types: see list of patent claims | Delivery; Device; Composition; |
Drugs Protected by US Patent 4,880,631
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 4,880,631
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Austria | 73322 | ⤷ Try a Trial | |||
| Australia | 2277388 | ⤷ Try a Trial | |||
| Australia | 604564 | ⤷ Try a Trial | |||
| Canada | 1320885 | ⤷ Try a Trial | |||
| Germany | 3869032 | ⤷ Try a Trial | |||
| Denmark | 529188 | ⤷ Try a Trial | |||
| European Patent Office | 0309051 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
