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Last Updated: April 19, 2024

Details for Patent: 4,377,584


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Summary for Patent: 4,377,584
Title: 4-Aza-17.beta.-substituted-5.alpha.-androstan-3-one-reductase inhibitors
Abstract:4-Aza-17.beta.-substituted-5.alpha.-androstan-3-ones and their A-homo analogs of the formula: ##STR1## where Formula (I) may also have the structure of partial Formulas (II) and/or (III); and pharmaceutically acceptable salts of the above compounds are active as testosterone 5.alpha.-reductase inhibitors, and thus useful topically for treatment of acne, seborrhea, female hirsutism, and systemically in treatment of benign prostatic hypertrophy.
Inventor(s): Rasmusson; Gary H. (Watchung, NJ), Johnston; David B. R. (Warren, NJ), Arth, deceased; Glen E. (late of Cranford, NJ)
Assignee: Merck & Co., Inc. (Rahway, NJ)
Application Number:06/189,981
Patent Claim Types:
see list of patent claims
Compound; Use; Dosage form; Composition;

Drugs Protected by US Patent 4,377,584

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 4,377,584

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 222390 ⤷  Try a Trial
Argentina 222391 ⤷  Try a Trial
Argentina 224011 ⤷  Try a Trial
Argentina 225045 ⤷  Try a Trial
Argentina 228037 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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