Details for Patent: 4,377,584
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Summary for Patent: 4,377,584
Title: | 4-Aza-17.beta.-substituted-5.alpha.-androstan-3-one-reductase inhibitors |
Abstract: | 4-Aza-17.beta.-substituted-5.alpha.-androstan-3-ones and their A-homo analogs of the formula: ##STR1## where Formula (I) may also have the structure of partial Formulas (II) and/or (III); and pharmaceutically acceptable salts of the above compounds are active as testosterone 5.alpha.-reductase inhibitors, and thus useful topically for treatment of acne, seborrhea, female hirsutism, and systemically in treatment of benign prostatic hypertrophy. |
Inventor(s): | Rasmusson; Gary H. (Watchung, NJ), Johnston; David B. R. (Warren, NJ), Arth, deceased; Glen E. (late of Cranford, NJ) |
Assignee: | Merck & Co., Inc. (Rahway, NJ) |
Application Number: | 06/189,981 |
Patent Claim Types: see list of patent claims | Compound; Use; Dosage form; Composition; |
Drugs Protected by US Patent 4,377,584
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International Family Members for US Patent 4,377,584
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Argentina | 222390 | ⤷ Try a Trial | |||
Argentina | 222391 | ⤷ Try a Trial | |||
Argentina | 224011 | ⤷ Try a Trial | |||
Argentina | 225045 | ⤷ Try a Trial | |||
Argentina | 228037 | ⤷ Try a Trial | |||
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