Details for Patent: 4,089,969
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Summary for Patent: 4,089,969
| Title: | 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof |
| Abstract: | Novel 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid compounds represented by the formula ##STR1## and the pharmaceutically acceptable, non-toxic esters and salts thereof, wherein R is hydrogen or a lower alkyl group containing from 1 to 4 carbon atoms and R.sup.1 is hydrogen, a lower alkyl group having from 1 to 4 carbon atoms, a lower alkoxy group of 1 to 4 carbon atoms, chloro, fluoro or bromo, the R.sup.1 substitution being at the ortho, meta or para positions of the aroyl group and process for the production of such compounds; 5-p-toluoyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid is representative of the class. These compounds, as the racemic mixture or the (1)-isomer, are useful as anti-inflammatory, analgesic and antipyretic agents and as smooth muscle relaxants. |
| Inventor(s): | Muchowski; Joseph M. (Mexico City, MX), Kluge; Arthur F. (Los Altos, CA) |
| Assignee: | Syntex (U.S.A.) Inc. (Palo Alto, CA) |
| Application Number: | 05/771,286 |
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Patent Claim Types: see list of patent claims | Compound; Use; Composition; Delivery; |
Drugs Protected by US Patent 4,089,969
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 4,089,969
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Argentina | 224997 | ⤷ Try a Trial | |||
| Austria | 363465 | ⤷ Try a Trial | |||
| Austria | 364844 | ⤷ Try a Trial | |||
| Austria | 369003 | ⤷ Try a Trial | |||
| Austria | A402479 | ⤷ Try a Trial | |||
| Austria | A509077 | ⤷ Try a Trial | |||
| Austria | A573780 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
