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Last Updated: March 29, 2024

Details for Patent: 6,361,795


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Title: Method for lowering blood glucose
Abstract:The invention disclosed comprises a method for administering the antidiabetic drug glipizide to a patient in need of glipizide in need of antidiabetic therapy.
Inventor(s): Kuczynski; Anthony L. (Mountain View, CA), Ayer; Atul Devolatt (Palo Alto, CA), Wong; Patrick S. L. (Palo Alto, CA)
Assignee: Alza Corporation (Mountain View, CA)
Filing Date:Jan 11, 1994
Application Number:08/180,409
Claims:1. A method for treating hyperglycemia in a patient, wherein the method comprises administering to the patient a dosage form comprising 2.0 mg to 750 mg of a glipizide composition that is administered at a dose of 10 ng to 25 mg per hour over an extended period of 24 hours, and wherein the method is characterized by administering the glipizide from a dosage form selected from the group consisting of an osmotic dosage form comprising a semipermeable polymer permeable to the passage of fluid, and a diffusion dosage form comprising a polymer that permits diffusion of glipizide through the polymer.

2. A method for lowering blood sugar in the treatment of a diabetic patient, which method comprises orally administering to the patient an effective blood sugar lowering dose of a composition comprising glipizide and a pharmaceutically acceptable carrier, which blood sugar lowering dose is administered by a method selected from the group consisting of osmosis comprising a semipermeable membrane, diffusion through a polymer permeable to glipizide, and ion-exchange over time to produce the intended lowering of the blood sugar in the patient.

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