Details for Patent: 5,681,545
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Title: | Medicinal aerosol formulations |
Abstract: | A self-propelling aerosol formulation which may be free from CFC's comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane. |
Inventor(s): | Purewal; Tarlochan S. (Leamington Spa, GB2), Greenleaf; David J. (Loughborough, GB2) |
Assignee: | Riker Laboratories, Inc. (St. Paul, MN) |
Filing Date: | May 31, 1995 |
Application Number: | 08/471,616 |
Claims: | 1. A method of making a suspension aerosol formulation suitable for delivery to the lung by inhalation comprising the steps of: (a) providing an aerosol container, and (b) charging to said container: (i) a medicament in an mount sufficient to provide a plurality of therapeutically effective doses, (ii) an amount of propellant sufficient to propel from said container said plurality of therapeutically effective doses, said propellant being substantially free of chlorofluorocarbons and comprising 1,1,1,2-tetrafluoroethane; and (c) dispersing said medicament. |