Details for Patent: 5,521,207
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| Title: | Substituted pyrazolyl benzenesulfonamide for the treatment of inflammation |
| Abstract: | A class of pyrazolyl benzenesulfonamide compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I: ##STR1## |
| Inventor(s): | Graneto; Matthew J. (St. Louis, MO) |
| Assignee: | G.D. Searle & Co. (Skokie, IL) |
| Filing Date: | Apr 06, 1994 |
| Application Number: | 08/223,629 |
| Claims: | 1. Compound which is 4-[5-(3-fluoro-4-methoxyphenyl)-3-(difluoromethyl)-1H-pyrazol-1-yl]benzene sulfonamide, or a pharmaceutically-acceptable salt thereof. 2. Pharmaceutical composition comprising a pharmaceutically-acceptable carrier or diluent and a therapeutically-effective amount of 4-[5-(3-fluoro-4-methoxylphenyl)-3(difluoromethyl)-1H-pyrazol-1-yl]benzene sulfonamide, or a pharmaceutically-acceptable salt thereof. 3. Method of treating inflammation or an inflammation-associated disorder, said method comprising administering to a subject having said inflammation or said inflammation-associated disorder, a therapeutically-effective amount of 4-[5-(3-fluoro-4-methoxyphenyl)-3-(difluoromethyl)-1H-pyrazol-1-yl]benzene sulfonamide, or a pharmaceutically-acceptable salt thereof. 4. The method of claim 3 for use in treatment of inflammation. 5. The method of claim 3 for use in treatment of an inflammation-associated disorder. 6. The method of claim 5 wherein the inflammation-associated disorder is arthritis. 7. The method of claim 5 wherein the inflammation-associated disorder is pain. 8. The method of claim 5 wherein the inflammation-associated disorder is fever. |
