Details for Patent: 5,508,260
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| Title: | Methods and compositions for treatment of diabetes mellitus, hypoglycemia, and other conditions |
| Abstract: | Methods for treatment of diabetes and other insulin-requiring conditions by administering insulin and a calcitonin with or without amylin, and methods for treatment of hypoglycemic conditions by administering a calcitonin alone or in combination with glucagon and/or an amylin, and related compositions. |
| Inventor(s): | Beaumont; Kevin (San Diego, CA), Young; Andrew A. (San Diego, CA) |
| Assignee: | Amylin Pharmaceuticals, Inc. (San Diego, CA) |
| Filing Date: | Jun 10, 1994 |
| Application Number: | 08/259,755 |
| Claims: | 1. A composition comprising a therapeutically effective amount of a calcitonin and an insulin admixed in a form suitable for therapeutic administration. 2. The composition of claim 1 wherein the effective amount of the calcitonin is about 0.01 mg to 1.0 mg. 3. The composition of claim 1 wherein said calcitonin is selected from the group consisting of calcitonins of avian origin and telost origin. 4. The composition of claim 1 wherein said calcitonin is chicken calcitonin. 5. The composition of claim 1 wherein the calcitonin is selected from the group consisting of eel calcitonin and salmon calcitonin. 6. The composition of claim 1 wherein the ratio of the therapeutically effective amount of the calcitonin and the therapeutically effective amount of the insulin is from about 1:1 to about 1:20. 7. The composition of claim 1 wherein said ratio is about 1:10. 8. The composition of claim 1 further comprising an amylin. |
