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Details for Generic Name: ticagrelor

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Ticagrelor is the generic ingredient in one branded drug marketed by Astrazeneca Lp and is included in one NDA. There are five patents protecting this compound and one Paragraph IV challenge. Additional information is available in the individual branded drug profile pages.

This ingredient has two hundred and thirteen patent family members in forty-four countries.

There are seventeen drug master file entries for ticagrelor. Three suppliers are listed for this compound.

Summary for Generic Name: ticagrelor

Drug Master File Entries: see list17
Suppliers / Packaging: see list7

Clinical Trials for: ticagrelor

High Ticagrelor Loading Dose in STEMI
Status: Completed Condition: Coronary Artery Disease

Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study
Status: Recruiting Condition: Unstable Angina Pectoris

Antiplatelet Effects of Ticagrelor Versus Clopidogrel in American Indian Patients
Status: Completed Condition: Coronary Artery Disease

Determine the Safety/Efficacy of Ticagrelor for Maintaining Patency of Arterio-Venous Fistulae Created for Hemodialysis
Status: Recruiting Condition: End Stage Renal Disease; Vascular Access Patency

Pharmacodynamic Evaluation of Switching From Prasugrel to Ticagrelor
Status: Completed Condition: Coronary Artery Disease; Acute Coronary Syndrome

Effects and Plasma Concentration of Ticagrelor, After Crushed and Non-crushed Intake, After Acute Coronary Syndrome
Status: Not yet recruiting Condition: Acute Coronary Syndrome

OraL Crushed and dIspersed Ticagrelor 180mg Compared to Whole Tablets of eQUal Dose in STEMI Patients unDergoing Primary PCI: a Pharmacokinetic/Pharmacodynamic Study (the LIQUID Study)
Status: Completed Condition: ST Elevation Myocardial Infarction

In Vitro Pharmacodynamic Effects of Cangrelor in Ticagrelor Treated Patients
Status: Completed Condition: Coronary Artery Disease

Cangrelor Ticagrelor Transition Study
Status: Completed Condition: Coronary Artery Disease

Ticagrelor Pharmacokinetics in NSTEMI
Status: Recruiting Condition: Myocardial Infarction

Courtesy of
See more clinical trials for this drug
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Astrazeneca Lp
TABLET;ORAL022433-002Sep 3, 2015RXNo<disabled><disabled>
Astrazeneca Lp
TABLET;ORAL022433-001Jul 20, 2011RXYes7,250,419<disabled>YY <disabled>
Astrazeneca Lp
TABLET;ORAL022433-002Sep 3, 2015RXNo8,425,934<disabled>Y <disabled>
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International Patent Family for Ingredient: ticagrelor

Country Document Number Publication Date
European Patent Office1289992Mar 15, 2006
China1334816Feb 06, 2002
Ukraine73181Apr 15, 2003
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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