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Details for Generic Name: vorinostat

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Vorinostat is the generic ingredient in one branded drug marketed by Merck and is included in one NDA. There are ten patents protecting this compound. Additional information is available in the individual branded drug profile pages.

There are two drug master file entries for vorinostat. One supplier is listed for this compound.

Summary for Generic Name: vorinostat

Tradenames:1
Patents:10
Applicants:1
NDAs:1
Drug Master File Entries: see list2
Suppliers: see list1
Therapeutic Class:Antineoplastics

Pharmacology for Ingredient: vorinostat

Clinical Trials for: vorinostat

Vorinostat Plus FND in Relapsed or Refractory Mantle Cell Lymphoma
Status: Not yet recruiting Condition: Mantle Cell Lymphoma

Phase 1 Study of Vorinostat and Bortezomib in Multiple Myeloma (MK-0683-015 EXT 1 (AM1))
Status: Completed Condition: Multiple Myeloma

Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases
Status: Active, not recruiting Condition: Brain Metastases

Study of Vorinostat (MK-0683) an HDAC Inhibitor, or Placebo in Combination With Bortezomib in Patients With Multiple Myeloma (MK-0683-088 AMN)
Status: Active, not recruiting Condition: Multiple Myeloma

A Pilot Study of Oral Vorinostat Plus Oral Eltrombopag Support in Patients With Lymphoma (VEIL)
Status: Terminated Condition: Follicular Lymphoma; Marginal Zone Lymphoma; Mantle Cell Lymphoma

MLN9708 and Vorinostat in Patients With Advanced p53 Mutant Malignancies
Status: Recruiting Condition: Advanced Cancers

SAHA + CHOP in Untreated T-cell Non-Hodgkin's Lymphoma
Status: Completed Condition: Lymphoma

High-Dose or Low-Dose Vorinostat in Combination With Carboplatin or Paclitaxel in Treating Patients With Advanced Solid Tumors
Status: Active, not recruiting Condition: Adult Solid Neoplasm

Vorinostat Plus Radiation Therapy in Pancreatic Cancer
Status: Terminated Condition: Pancreatic Cancer

Ph I Vorinostat in the Treatment of Advanced Staged Oropharyngeal Squamous Cell Carcinoma
Status: Recruiting Condition: Stage III Squamous Cell Carcinoma of the Oropharynx; Stage IV Squamous Cell Carcinoma of the Oropharynx

Courtesy of ClinicalTrials.org
See more clinical trials for this drug
Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Merck
ZOLINZA
vorinostat
CAPSULE;ORAL021991Oct 6, 2006RXYes8,067,472<disabled><disabled>
Merck
ZOLINZA
vorinostat
CAPSULE;ORAL021991Oct 6, 2006RXYes8,093,295<disabled>Y<disabled>
Merck
ZOLINZA
vorinostat
CAPSULE;ORAL021991Oct 6, 2006RXYes8,101,663<disabled><disabled>
Merck
ZOLINZA
vorinostat
CAPSULE;ORAL021991Oct 6, 2006RXYes7,456,219<disabled>Y<disabled>
Merck
ZOLINZA
vorinostat
CAPSULE;ORAL021991Oct 6, 2006RXYes7,652,069<disabled>Y<disabled>
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