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Details for Generic Name: perflutren

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Perflutren is the generic ingredient in one branded drug marketed by Lantheus Medcl and is included in one NDA. There are four patents protecting this compound. Additional information is available in the individual branded drug profile pages.

This ingredient has one hundred and eight patent family members in thirty countries.

One supplier is listed for this compound.

Summary for Generic Name: perflutren

Tradenames:1
Patents:4
Applicants:1
NDAs:1
Drug Master File Entries: 0
Suppliers: see list1
Formulation / Manufacturing:see details

Pharmacology for Ingredient: perflutren

Clinical Trials for: perflutren

A Prospective, Phase IV, Surveillance Registry Study to Evaluate the Safety of DEFINITY® in Clinical Practice
Status: Completed Condition: Cardiovascular Disease

Evaluation of Intra-operative Ultrasound Contrast Enhancement in the Evaluation of Liver Tumors
Status: Terminated Condition: Liver Tumors

A Study of Commercial DEFINITY® to Monitor the Effects of the Heart's Pulmonary Artery Pressure
Status: Completed Condition: Pulmonary Heart Disease

3-D Transcranial Ultrasound Analysis Study
Status: Completed Condition: Cerebrovascular Accident; Intracranial Hypertension

Feasibility of Ultrasound Microbubble Contrast-Enhanced (CEUS) Sentinel Lymph Node Imaging With Guided Biopsy in Breast Cancer Patients
Status: Not yet recruiting Condition: Breast Cancer

Breast VCEUS to Evaluate Early Response to Neoadjuvant Chemotherapy
Status: Not yet recruiting Condition: Breast Cancer

Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular Age-related Macular Degeneration
Status: Recruiting Condition: Exudative Macular Degeneration; Retinal Hemorrhage

Estimation of Pulmonary Vascular Resistance by Contrast Echocardiography
Status: Completed Condition: Pulmonary Arterial Hypertension

MRI / Ultrasound Fusion With Contrast-Enhanced Ultrasound Guidance
Status: Active, not recruiting Condition: Prostatic Neoplasms

Microbubble-Enhanced Clotbust Treatment of Acute Ischemic Stroke
Status: Terminated Condition: Acute Ischemic Stroke

Courtesy of ClinicalTrials.org
See more clinical trials for this drug
Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Lantheus Medcl
DEFINITY
perflutren
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes6,033,645<disabled><disabled>
Lantheus Medcl
DEFINITY
perflutren
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes8,685,441<disabled><disabled>
Lantheus Medcl
DEFINITY
perflutren
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes5,527,521<disabled>Y<disabled>
Lantheus Medcl
DEFINITY
perflutren
INJECTABLE;INTRAVENOUS021064-001Jul 31, 2001RXYes8,658,205<disabled>Y<disabled>
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International Patent Family for Ingredient: perflutren

Country Document Number Publication Date
European Patent Office1444991Aug 11, 2004
Slovenia1419789Mar 31, 2010
China1149259May 07, 1997
Japan2000513357Oct 10, 2000
Canada2191079Nov 30, 1995
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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