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Details for Generic Name: aprepitant

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Aprepitant is the generic ingredient in two branded drugs marketed by Sandoz and Merck, and is included in two NDAs. There are three patents protecting this compound and three Paragraph IV challenges. Additional information is available in the individual branded drug profile pages.

This ingredient has one hundred and seventy-three patent family members in fifty-two countries.

There are eighteen drug master file entries for aprepitant. Three suppliers are listed for this compound.

Summary for Generic Name: aprepitant

Tradenames:2
Patents:3
Applicants:2
NDAs:2
Drug Master File Entries: see list18
Suppliers / Packaging: see list13
Therapeutic Class:Antiemetics
Formulation / Manufacturing:see details

Clinical Trials for: aprepitant

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Merck
EMEND
aprepitant
CAPSULE;ORAL021549-002Mar 26, 2003RXYes8,258,132<disabled>Y<disabled>
Sandoz
APREPITANT
aprepitant
CAPSULE;ORAL090999-003Sep 24, 2012RXNo<disabled><disabled>
Sandoz
APREPITANT
aprepitant
CAPSULE;ORAL090999-002Sep 24, 2012RXNo<disabled><disabled>
Merck
EMEND
aprepitant
CAPSULE;ORAL021549-003Jun 30, 2006RXNo5,719,147<disabled>YY<disabled>
Merck
EMEND
aprepitant
CAPSULE;ORAL021549-001Mar 26, 2003RXNo6,096,742<disabled>YY<disabled>
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International Patent Family for Ingredient: aprepitant

Country Document Number Publication Date
Turkey9903299Jul 21, 2000
China100352443Dec 05, 2007
Poland369887May 02, 2005
China1142819Feb 12, 1997
Slovenia1455756Dec 31, 2008
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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.

Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided information. There is no warranty that the information contained herein is error free. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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