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Details for Generic Name: aprepitant

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Summary for Generic Name: aprepitant

Drug Master File Entries: see list15
Suppliers: see list3
Therapeutic Class:Antiemetics

Clinical Trials for: aprepitant

Efficacy of Aprepitant (Emend®) in Children
Status: Recruiting Condition: Nausea; Vomiting; Childhood Cancer

A Study of MK-0869 (Aprepitant) and MK-0517 (Fosaprepitant) in Pediatric Participants Receiving Chemotherapy (MK-0869-134)
Status: Terminated Condition: Chemotherapy-Induced Nausea and Vomiting

Aprepitant's Effect on Drug Metabolism in Multi-Day Combination (CHOP/R-CHOP) Chemotherapy Regimen in Lymphoma Patients
Status: Completed Condition: Lymphoma

Topical Aprepitant in Prurigo Patients
Status: Completed Condition: Pruritus

A Study of Aprepitant (MK-0869) in Pediatric Participants Undergoing Surgery (MK-0869-148)
Status: Completed Condition: Postoperative Nausea and Vomiting

Aprepitant Effects on Oxycodone Response
Status: Completed Condition: Narcotic Abuse

Study to Evaluate Anti-emetic Effect of Aprepitant Versus Placebo in Children and Adolescent Receiving Chemotherapy
Status: Completed Condition: Chemotherapy Induced Nausea and Vomiting

Safety and Efficacy of Aprepitant, Ramosetron, and Dexamethasone for Chemotherapy-Induced Nausea and Vomiting in Patients With Ovarian Cancer Treated With Taxane/Carboplatin
Status: Completed Condition: Chemotherapy-Induced Nausea and Vomiting; Ovarian Cancer

A Study to Assess the Bioequivalence of Aprepitant and Fosaprepitant and the Effect of Food on Aprepitant Bioavailability (0869-165)
Status: Completed Condition: Chemotherapy-Induced Nausea and Vomiting

Pharmacokinetic (PK) Characteristics and Anti-Inflammatory Effects of the NK-1R Antagonist, Aprepitant, In HIV-Infected Subjects With Undetectable Viral Load Receiving Atazanavir/Ritonavir Or Darunavir/Ritonavir-Containing Antiretroviral Therapy
Status: Recruiting Condition: HIV Infection

Courtesy of
See more clinical trials for this drug
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
CAPSULE;ORAL021549Jun 30, 2006RXNo8,258,132<disabled>Y<disabled>
CAPSULE;ORAL021549Mar 26, 2003RXYes8,258,132<disabled>Y<disabled>
CAPSULE;ORAL090999Sep 24, 2012RXNo<disabled><disabled>
CAPSULE;ORAL021549Mar 26, 2003RXNo8,258,132<disabled>Y<disabled>
CAPSULE;ORAL021549Mar 26, 2003RXNo6,096,742<disabled>YY<disabled>
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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