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Details for Generic Name: alvimopan

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Alvimopan is the generic ingredient in one branded drug marketed by Cubist Pharms and is included in one NDA. There are five patents protecting this compound. Additional information is available in the individual branded drug profile pages.

This ingredient has fifty patent family members in twenty-eight countries.

There are two drug master file entries for alvimopan. One supplier is listed for this compound.

Summary for Generic Name: alvimopan

Tradenames:1
Patents:5
Applicants:1
NDAs:1
Drug Master File Entries: see list2
Suppliers / Packaging: see list1
Formulation / Manufacturing:see details

Pharmacology for Ingredient: alvimopan

Drug ClassOpioid Antagonist
Mechanism of ActionOpioid Antagonists

Clinical Trials for: alvimopan

Alvimopan and Ileus in PSF
Status: Recruiting Condition: Ileus; Spinal Fusion

A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy
Status: Completed Condition: Postoperative Ileus

Clinical Outcomes After Bowel Resection in Patients Receiving Alvimopan Versus Patients Not Receiving Alvimopan in the Premier Perspective Database
Status: Completed Condition: Ileus

Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
Status: Completed Condition: Bowel Dysfunction; Constipation

Gastrointestinal Tract Recovery in Patients Undergoing Open Ventral Hernia Repair
Status: Recruiting Condition: Ventral Hernia

Intermountain Healthcare's Enhanced Recovery Protocol for Colon Surgery With and Without Alvimopan Use
Status: Completed Condition: Ileus

Entereg Laparoscopic Colon Resection Study
Status: Recruiting Condition: Laparoscopic Colonic Resection

Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
Status: Completed Condition: Bowel Dysfunction; Constipation

Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
Status: Completed Condition: Bowel Dysfunction; Constipation

Study Of Alvimopan Drug For Treatment Of Constipation Due To Prescription Pain Medication
Status: Completed Condition: Constipation; Bowel Dysfunction

Courtesy of ClinicalTrials.org
See more clinical trials for this drug
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Cubist Pharms
ENTEREG
alvimopan
CAPSULE;ORAL021775-001May 20, 2008RXYes8,946,262<disabled><disabled>
Cubist Pharms
ENTEREG
alvimopan
CAPSULE;ORAL021775-001May 20, 2008RXYes6,469,030<disabled><disabled>
Cubist Pharms
ENTEREG
alvimopan
CAPSULE;ORAL021775-001May 20, 2008RXYes8,112,290<disabled><disabled>
Cubist Pharms
ENTEREG
alvimopan
CAPSULE;ORAL021775-001May 20, 2008RXYes<disabled><disabled>
Cubist Pharms
ENTEREG
alvimopan
CAPSULE;ORAL021775-001May 20, 2008RXYes8,645,160<disabled><disabled>
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International Patent Family for Ingredient: alvimopan

Country Document Number Publication Date
Norway921182Sep 30, 1992
European Patent Office0506478Sep 30, 1992
Brazil9201084Nov 24, 1992
Denmark0506478Oct 20, 1997
Spain2329004Nov 20, 2009
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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