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Details for Generic Name: acetazolamide

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Acetazolamide is the generic ingredient in three branded drugs marketed by Zydus Pharms Usa Inc, Alra, Lannett, Teva Branded Pharm, Mutual Pharm, Sun Pharm Inds, Vangard, Heritage Pharms Inc, Watson Labs, Ascot, Taro, Hospira, Sagent Agila, X Gen Pharms, Teva Womens, Eurohlth Intl Sarl, and Emcure Pharms Ltd, and is included in nineteen NDAs. Additional information is available in the individual branded drug profile pages.

There are ten drug master file entries for acetazolamide. Three suppliers are listed for this compound.

Summary for Generic Name: acetazolamide

Drug Master File Entries: see list10
Suppliers / Packaging: see list3
Therapeutic Class:Ophthalmic Agents

Pharmacology for Ingredient: acetazolamide

Clinical Trials for: acetazolamide

A Single-center Pilot Study Evaluating the Immediate Effects of Low-dose Acetazolamide on Respiratory Control in Subjects With Treatment Emergent Sleep Disordered Breathing
Status: Recruiting Condition: Sleep Apnea

Effect of Acetazolamide on Central Sleep Apnea Related to Opium Consumption
Status: Recruiting Condition: Central Sleep Apnea, Secondary

Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure
Status: Recruiting Condition: Heart Failure

Effect of Acetazolamide & Position in CSF Leakage and Collection and Wound Dehiscence
Status: Recruiting Condition: Fibrolipoma of Filum Terminale; Lipomyelomeningocele; Split Cord Malformation; Dermal Sinus; Tethered Cord Syndrome; Tumor

Acetazolamide for the Prevention of High Altitude Illness: a Comparison of Dosing
Status: Recruiting Condition: Prophylaxis of Acute Mountain Sickness

A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction
Status: Recruiting Condition: Obstructive Sleep Apnea; Sleep-Disordered Breathing; Blood Pressure; Hypertension

Effect of Acetazolamide and Furosemide on Obesity-induced Glomerular Hyperfiltration
Status: Completed Condition: Obesity-induced Hyperfiltration

Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery
Status: Recruiting Condition: Thoracic Aneurysm

Comparison of Temazepam and Acetazolamide to Treat Difficulty Sleeping at High Altitude
Status: Completed Condition: High-altitude Sleep Disturbance

Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention
Status: Completed Condition: Pulmonary Edema; Cerebral Edema

Acetazolamide Facilitates Ventilator Weaning
Status: Recruiting Condition: Ventilator Weaning; Alkalosis, Metabolic

Acetazolamide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow
Status: Completed Condition: Headache; Migraine

Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.
Status: Completed Condition: Pulmonary Disease, Chronic Obstructive; Obesity Hypoventilation Syndrome; Metabolic Alkalosis

Role of Acetazolamide and Hydrochlorothiazide Followed by Furosemide in Treating Nephrotic Edema
Status: Completed Condition: Nephrotic Syndrome; Edema

Continuous Positive Airway Pressure and Acetazolamide to Treat Sleep Apnea Syndrome Patients at Altitude
Status: Completed Condition: Obstructive Sleep Apnea Syndrome

Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis for Ocular Hypertension Control After Intravitreal Bevacizumab
Status: Completed Condition: Age Related Macular Degeneration; Diabetic Retinopathy

Comparison Between Effect of Acetazolamide and NaHco3 in Prevention of Contrast Nephropathy
Status: Completed Condition: Contrast Induced Nephropathy

Effects of Acetazolamide and CO2 Inhalation on Exercise-induced Periodic Breathing in Heart Failure
Status: Completed Condition: Chronic Heart Failure

Effectiveness of Acetazolamide for Reversal of Metabolic Alkalosis in Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
Status: Completed Condition: Decompensated Chronic Obstructive Pulmonary Disease

Predicting Successful Sleep Apnea Treatment With Acetazolamide in Heart Failure Patients
Status: Recruiting Condition: Heart Failure;; Controls Without Heart Failure

Interactions Between Intravenous Cocaine and Acetazolamide or Quinine
Status: Completed Condition: Cocaine Use; Pharmacokinetics

Acetazolamide for Respiratory Failure in Combination With Metabolic Alkalosis
Status: Completed Condition: Respiratory Insufficiency; Alkalosis

Treatment of High Altitude Polycythemia by Acetazolamide
Status: Completed Condition: High Altitude Polycythemia

Effectiveness of Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis in Intraocular Pressure (IOP) After Bevacizumab
Status: Completed Condition: Macular Edema; Diabetic Retinopathy; Macular Degeneration

Study of Cobalt's Role in Excessive Erythrocytosis Among High Altitude Dwellers in Cerro de Pasco, Peru
Status: Completed Condition: Erythrocytosis; Mountain Sickness

Carbonic Anhydrase Antagonism in Subarachnoid Hemorrhage
Status: Withdrawn Condition: Acute Cerebrovascular Accident; Vasospasm

A Trial of Acetazolamide Versus Placebo in Preventing Mountain Sickness During Rapid Ascent
Status: Completed Condition: Acute Mountain Sickness

Comparing Eye Pressure Using Maximal Tolerated Local Therapy or Systemic Acetazolamide
Status: Completed Condition: Control of Elevated Eye Pressure by Local and Systemic Therapy

The Role of Enhanced Cerebral Perfusion in Lesion Evolution
Status: Not yet recruiting Condition: Multiple Sclerosis

Effect of Potassium and Acetazolamide on People With Andersen-Tawil Syndrome
Status: Terminated Condition: Andersen-Tawil Syndrome

Idiopathic Intracranial Hypertension Treatment Trial
Status: Completed Condition: Idiopathic Intracranial Hypertension

Altitude Sickness Prevention and Efficacy of Comparative Treatments
Status: Not yet recruiting Condition: Acute Mountain Sickness

Effects of Dual Cyclooxygenase-2 and Carbonic Anhydrase Inhibition
Status: Terminated Condition: Healthy Volunteers

COSOPT-S® Treatment Versus Acetazolamide Before Trabeculectomy
Status: Completed Condition: Glaucoma

A Randomized, Open-label Study on Helicobacter Pylori Eradication With Standard Triple Regimen Plus Acetazolamide
Status: Withdrawn Condition: H. Pylori Infection

Assessing the Effectiveness and Safety of the ID-Cap System for Medication Monitoring and Adherence
Status: Not yet recruiting Condition: Marijuana Dependence

Normal Pressure Hydrocephalus Treatment by Acetazolamide
Status: Not yet recruiting Condition: Motor Condition.; Cognitive Investigation

Treatment of Sleep Related Breathing Disorders in Patients With Pulmonary Hypertension
Status: Completed Condition: Pulmonary Hypertension; Breathing-Related Sleep Disorder

Intracranial Pressure in Experimental Models of Headache
Status: Completed Condition: High Altitude Headache

Effect of Antiglaucoma Agents on Short Term Intraocular Pressure Fluctuations After Intravitreal Bevacizumab Injection
Status: Completed Condition: Intraocular Pressure Change in Intravitreal Injection

Treatment of Patients With the Obstructive Sleep Apnea Syndrome at Altitude
Status: Completed Condition: Obstructive Sleep Apnea Syndrome

Randomized Trial of Acetazolamide for Uveitis-Associated Cystoid Macular Edema
Status: Completed Condition: Macular Edema, Cystoid

Immediate Anterior Chamber Paracentesis With A 30-Gauge Needle for Acute Primary Angle - Closure
Status: Completed Condition: Glaucoma, Angle-closure

A Combined Surgical and Medical Approach in Mild Sleep Apnea
Status: Recruiting Condition: Sleep Apnea

Buspirone as a Potential Treatment for Recurrent Central Apnea
Status: Terminated Condition: Central Apnea; Heart Failure

Treatment of Orthostatic Intolerance
Status: Active, not recruiting Condition: Tachycardia; Chronic Orthostatic Intolerance

Evaluation of a Compliance Marker in Prescription Opioid Abusers With Chronic Pain
Status: Not yet recruiting Condition: Compliance; Chronic Pain

The Effect of Glyceryl Trinitate and Diamox on Cerebral Haemodynamics.
Status: Not yet recruiting Condition: Migraine

Treatment of Orthostatic Hypotension in Autonomic Failure
Status: Recruiting Condition: Autonomic Failure; Orthostatic Hypotension

Stop Retinal Ganglion Cell Dysfunction Study
Status: Recruiting Condition: Glaucoma

Sleep Apnea: Mechanism and Cerebrovascular Consequences
Status: Withdrawn Condition: Sleep Apnea, Obstructive; Stroke

Use of an Ocular Telemetry Sensor in Diamox Treated Patients
Status: Completed Condition: Glaucoma; Ocular Hypertension

Effect of GTN and Diamox Measured by BOLD-Response.
Status: Recruiting Condition: Healthy

Study of Brain Blood Flow During Induced Hypercapnia (Excess Blood Carbon Dioxide)
Status: Completed Condition: Healthy; Hypercapnia

Effects of Potassium Citrate in Urine of Children With Elevated Calcium in Urine and Kidney Stones
Status: Completed Condition: Kidney Calculi

ALPI vs Medical Therapy Effects on Optic Nerve Structure & Function
Status: Recruiting Condition: Glaucoma

EAGLE - Multicenter Study of the European Assessment Group for Lysis in the Eye
Status: Terminated Condition: Retinal Artery Occlusion; Fibrinolysis; Visual Acuity; Stroke; Hemodilution

Effect of Prophylactic Aqueous Suppression on Hyperencapsulation of Ahmed Glaucoma Valves
Status: Recruiting Condition: Glaucoma

4-Aminopyridine in Episodic Ataxia Type 2
Status: Enrolling by invitation Condition: Episodic Ataxia Type 2

Effect of Furosemide on Obesity-induced Glomerular Hyperfiltration
Status: Terminated Condition: Obesity-induced Hyperfiltration

Histamine Glutamate Antagonism in Stroke
Status: Completed Condition: Acute Cerebrovascular Accident; Cerebral Edema

Ibuprofen vs Acetaminophen for AMS Prevention
Status: Active, not recruiting Condition: Acute Mountain Sickness, Blood Oxygen Saturation, Headache

Evaluation of the Prevention and Treatment Effects of Chinese Medicine on High Altitude Illness
Status: Not yet recruiting Condition: Acute Mountain Sickness (AMS)

Low Salt Diet in Idiopathic Hypercalciuria
Status: Completed Condition: Hypercalciuria

Long-term Treatment Effect of Intravitreal Ant-VEGF in Branch Retinal Vein Occlusion
Status: Completed Condition: Branch Retinal Vein Occlusion

Determinants of Cognitive Impairment After Acute Coronary Syndrome
Status: Completed Condition: Coronary Syndrome

Ketogenic Diet vs.Antiepileptic Drug Treatment in Drug Resistant Epilepsy
Status: Active, not recruiting Condition: Epilepsy; Mental Retardation

Courtesy of
See more clinical trials for this drug
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Watson Labs
TABLET;ORAL088882-001Oct 22, 1985DISCNNo<disabled><disabled>
Emcure Pharms Ltd
acetazolamide sodium
INJECTABLE;INJECTION202693-001Dec 19, 2014RXNo<disabled><disabled>
TABLET;ORAL087654-001Feb 5, 1982DISCNNo<disabled><disabled>
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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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