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Details for Patent: 6,280,704

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Summary for Patent: 6,280,704

Title: Ultrasonic imaging system utilizing a long-persistence contrast agent
Abstract:A microbubble preparation formed of a plurality of microbubbles comprising a first gas and second gas surrounded by a membrane such as a surfactant, wherein the first gas and the second gas are present in a molar ration of from about 1:100 to abut 1000:1, and wherein the first gas has a vapor pressure of at least about (760-X) mm Hg at 37.degree. C., where x is the vapor pressure of the second gas at 37.degree. C., and wherein the vapor pressure of each of the first and second gases is greater than about 75 mm Hg at 37.degree. C.; also disclosed are methods for preparing microbubble compositions, including compositions that rapidly shrink from a first average diameter to a second average diameter less than about 75% of the first average diameter and are stabilized at the second average diameter; methods and kits for preparing microbubbles; and methods for using such microbubbles as contrast agents.
Inventor(s): Schutt; Ernest G. (San Diego, CA), Anderson; Charles David (Lebanon, NJ), Evitts; David P. (La Jolla, CA)
Assignee: Alliance Pharmaceutical Corp. (SAn Diego, CA)
Application Number:08/986,879
Patent Claim Types:
see list of patent claims
Device; Dosage form; Compound;
Patent Metrics:
Source: PatentQuant.com
Field: Medical technology
Back Citations: 99th percentile
Forward Citations: 0th percentile
Patent PDF download available with subscription

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Premature patent expiration for: 6,280,704

Expiration due to failure to pay maintenance fee

Patent Number Expiration Date
6,280,704 August 28, 2013

International Patent Family for Patent: 6,280,704

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Hungary9802095<disabled in preview>
JapanH09501164<disabled in preview>
Japan3559849<disabled in preview>
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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