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|Title:||Multivesicular liposomes with controlled release of encapsulated biologically active substances|
|Abstract:||A multivesicular liposome composition containing at least one acid other than a hydrohalic acid and at least one biologically active substance, the vesicles having defined size distribution, adjustable average size, internal chamber size and number, provides a controlled release rate of the biologically active substance from the composition. A process for making the composition features addition of a non-hydrohalic acid effective to sustain and control the rate of release of an encapsulated biologically active substance from the vesicles at therapeutic levels in vivo.|
|Inventor(s):||Sankaram; Mantripragada Bhima (San Diego, CA), Kim; Sinil (Solana Beach, CA)|
|Assignee:||SkyePharma Inc. (San Diego, CA)|
Patent Claim Types:|
see list of patent claims
|Use; Dosage form; Device;|
Field: Not categorized
Back Citations: 26th percentile
Forward Citations: 2nd percentile
|Country||Document Number||Estimated Expiration||Supplementary Protection Certificate||SPC Country||SPC Expiration|
|Austria||196248||<disabled in preview>|
|Australia||1053595||<disabled in preview>|
|Australia||686277||<disabled in preview>|
| This preview shows a limited data set|
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.
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