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Details for Patent: 5,538,982

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Summary for Patent: 5,538,982

Title: Medical use for tachykinin antagonists
Abstract:The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their preparation, pharmaceutical compositions containing them and their medical use. ##STR1## wherein R represents the ring A ##STR2## or 2-pyridinyl or 2-pyridinyl-N-oxide; R.sup.1 is selected from halogen atoms and C.sub.1-4 alkyl, C.sub.1-4 alkoxy, trifluoromethyl, and S(O).sub.n C.sub.1-4 alkyl groups; R.sup.2 and R.sup.3, which may be the same or different, each independently are selected from hydrogen and halogen atoms and C.sub.1-4 alkyl, C.sub.1-4 alkoxy, trifluoromethyl and cyano groups; n represents zero, 1 or 2; and pharmaceutically acceptable salts and solvates thereof.
Inventor(s): Hagan; Russell M. (Ware, GB), Bunce; Keith T. (Ware, GB)
Assignee: Glaxo Group Limited (London, GB2)
Application Number:08/269,079
Patent Claim Types:
see list of patent claims
Use; Compound;
Patent PDF download available with subscription

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Foreign Priority and PCT Information for Patent: 5,538,982

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9120172Sep 20, 1991
United Kingdom9202839Feb 11, 1992
United Kingdom9204151Feb 27, 1992

International Patent Family for Patent: 5,538,982

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria195867<disabled in preview>
Australia2458392<disabled in preview>
Australia657996<disabled in preview>
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