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Details for Patent: 5,480,656

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Summary for Patent: 5,480,656

Title: Prolonged release microcapsules
Abstract:This invention provides a microcapsule designed for zero order release of a physiologically active polypeptide over a period of at least two months, which is produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing about 20 to 70% (w/w) of said polypeptide and an oil layer containing a copolymer or homopolymer having a weight-average molecular weight of 7,000 to 30,000, wherein the composition ratio of lactic acid/glycolic acid in the copolymer or homopolymer is 80/10 to 100/0, and then subjecting said water-in oil emulsion to microencapsulation.
Inventor(s): Okada; Hiroaki (Suita, JP), Inoue; Yayoi (Kyoto, JP), Ogawa; Yasuaki (Otokuni, JP)
Assignee: Takeda Chemical Industries, Ltd. (Osaka, JP)
Application Number:08/188,918
Patent Claim Types:
see list of patent claims
Compound; Dosage form;
Patent PDF download available with subscription

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Foreign Priority and PCT Information for Patent: 5,480,656

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2-033133Feb 13, 1990

International Patent Family for Patent: 5,480,656

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria123413<disabled in preview>
Australia645108<disabled in preview>
Australia8179491<disabled in preview>
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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