Details for Patent: 7,658,945
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Which drugs does patent 7,658,945 protect, and when does it expire?
Patent 7,658,945 protects INTERMEZZO and is included in one NDA.
This patent has twenty-one patent family members in twelve countries.
Summary for Patent: 7,658,945
| Title: | Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof |
| Abstract: | The present invention provides novel compositions for the delivery of a hypnotic agent across the oral mucosa. In particular, the buffer system in the compositions of the present invention raises the pH of saliva to a pH greater than about 7.8, thereby facilitating the substantially complete conversion of the hypnotic agent from its ionized to its un-ionized form. As a result, the dose of hypnotic agent is rapidly and efficiently absorbed by the oral mucosa with surprisingly low inter-subject variability. Furthermore, delivery of the hypnotic agent across the oral mucosa advantageously bypasses hepatic first pass metabolism of the drug and avoids enzymatic degradation of the drug within the gastrointestinal tract. Methods for using the compositions of the present invention for treating sleep disorders such as insomnia are also provided. |
| Inventor(s): | Singh; Nikhilesh N. (Mill Valley, CA) |
| Assignee: | Transcept Pharmaceuticals, Inc. (Pt. Richmond, CA) |
| Application Number: | 11/060,641 |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 7,658,945 |
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Patent Claim Types: see list of patent claims | Use; Composition; Dosage form; |
Drugs Protected by US Patent 7,658,945
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Purdue Pharma | INTERMEZZO | zolpidem tartrate | TABLET;SUBLINGUAL | 022328-001 | Nov 23, 2011 | DISCN | Yes | No | ⤷ Try a Trial | ⤷ Try a Trial | Y | METHOD FOR TREATING INSOMNIA | ⤷ Try a Trial | |||
| Purdue Pharma | INTERMEZZO | zolpidem tartrate | TABLET;SUBLINGUAL | 022328-002 | Nov 23, 2011 | DISCN | Yes | No | ⤷ Try a Trial | ⤷ Try a Trial | Y | METHOD FOR TREATING INSOMNIA | ⤷ Try a Trial | |||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 7,658,945
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Australia | 2005215782 | ⤷ Try a Trial | |||
| Brazil | PI0507733 | ⤷ Try a Trial | |||
| Canada | 2556450 | ⤷ Try a Trial | |||
| Canada | 2816904 | ⤷ Try a Trial | |||
| China | 100548281 | ⤷ Try a Trial | |||
| China | 1929822 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
