Details for Patent: 6,607,748
✉ Email this page to a colleague
Summary for Patent: 6,607,748
| Title: | Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture |
| Abstract: | The present invention relates to a novel form of cross-linked high amylose starch and processes for its manufacture. Such cross-linked high amylose starch is useful as an excipient in a controlled-release pharmaceutical formulation when compressed with pharmaceutical agent(s) in a tablet. Such cross-linked high amylose starch is prepared by (a) cross-linking and chemical modification of high amylose starch, (b) gelatinization, and (c) drying to obtain a powder of said controlled release excipient. In a preferred embodiment, such cross-linked high amylose starch is prepared in the following steps: (1) granular cross-linking and additional chemical modification (e.g., hydroxypropylation) of high-amylose starch; (2) thermal gelatinization of the starch from step (1); and (3) drying the starch from step (2) to yield a powder capable of being used as a controlled release excipient. |
| Inventor(s): | Lenaerts; Vincent (Montreal (Quebec), CA), Beck; Roland Herwig Friedrich (Valparaiso, IN), Van Bogaert; Elsie (B-2880 Bornem, BE), Chouinard; Francois (Lorriane (Quebec), CA), Hopcke; Reiner (D-47533 Kleve, DE), Desevaux; Cyril (Saint-Hubert (Quebec), CA) |
| Assignee: | |
| Application Number: | 09/606,399 |
|
Patent Claim Types: see list of patent claims | Composition; Compound; Dosage form; Process; Use; |
Drugs Protected by US Patent 6,607,748
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 6,607,748
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Argentina | 029549 | ⤷ Try a Trial | |||
| Austria | 328585 | ⤷ Try a Trial | |||
| Australia | 2001271481 | ⤷ Try a Trial | |||
| Australia | 7148101 | ⤷ Try a Trial | |||
| Brazil | 0112140 | ⤷ Try a Trial | |||
| Canada | 2414349 | ⤷ Try a Trial | |||
| China | 100352509 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
