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Last Updated: April 25, 2024

Details for Patent: 6,417,191

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Summary for Patent: 6,417,191

Title:	Synergistic combinations of zidovudine, 1592U89 and 3TC
Abstract:	The present invention relates to therapeutic combinations of (1S,4R)-cis-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene- 1-methanol (1592U89), 3'-azido-3'-deoxythymidine (zidovudine) and (2R,cis)-4-amino-]-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin- 2-one (3TC) (or, alternatively to 3TC, (2R,cis)-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyr imidin-2-one (FTC)) which have anti-HIV activity. The present invention is also concerned with pharmaceutical compositions containing said combinations and their use in the treatment of HIV infections including infections with HIV mutants bearing resistance to nucleoside and/or non-nucleoside inhibitors.
Inventor(s):	Barry; David Walter (Chapel Hill, NC), St. Clair; Martha Heider (Rougemont, NC)
Assignee:	GlaxoSmithKline (Research Triangle Park, NC)
Application Number:	08/930,225
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 6,417,191
Patent Claim Types: see list of patent claims	Use; Dosage form; Formulation; Composition;

Drugs Protected by US Patent 6,417,191

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

Foreign Priority and PCT Information for Patent: 6,417,191

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
United Kingdom	9506489	Mar 30, 1995
United Kingdom	9506490	Mar 30, 1995

PCT Information
PCT Filed	March 28, 1996	PCT Application Number:	PCT/EP96/01352
PCT Publication Date:	October 03, 1996	PCT Publication Number:	WO96/30025

International Family Members for US Patent 6,417,191

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
African Regional IP Organization (ARIPO)	652	⤷ Try a Trial
African Regional IP Organization (ARIPO)	9701089	⤷ Try a Trial
Austria	220551	⤷ Try a Trial
Australia	5497296	⤷ Try a Trial
Australia	715213	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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