Details for Patent: 5,948,438
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Summary for Patent: 5,948,438
Title: | Pharmaceutical formulations having improved disintegration and/or absorptivity |
Abstract: | An oral solid dosage form, comprising a compressed tablet including an excipient comprising (a) microcrystalline cellulose; and (b) a compressibility augmenting agent which (I) physically restricts the proximity of the interface between adjacent cellulose surfaces (e.g., silicon dioxide); or (ii) inhibits interactions between adjacent cellulose surfaces (e.g., sodium lauryl sulfate); or (iii) accomplishes both (i) and (ii) above; together with an active agent, is disclosed which provides improved disintegration and/or absorptivity to the oral solid dosage form when orally administered to human patients. The excipient comprises agglomerated particles of said microcrystalline cellulose and said compressibility augmenting agent in intimate association with each other. |
Inventor(s): | Staniforth; John N. (Bath, GB), Sherwood; Bob E. (Amenia, NY), Hunter; Edward A. (Glenham, NY) |
Assignee: | Edward Mendell Co., Inc. (Patterson, NY) |
Application Number: | 08/868,744 |
Patent Claim Types: see list of patent claims | Dosage form; Composition; |
Drugs Protected by US Patent 5,948,438
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 5,948,438
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Austria | 239450 | ⤷ Try a Trial | |||
Austria | 441403 | ⤷ Try a Trial | |||
Austria | 445391 | ⤷ Try a Trial | |||
Australia | 4759896 | ⤷ Try a Trial | |||
Australia | 5019996 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |