Details for Patent: 5,849,803

Title:	Method of treating erectile dysfunction with nitroglycerine
Abstract:	Lipophilic active substance composition and its use in a new method of treating erectile dysfunction by administration of nitroglycerine together with a hydrophilic vehicle and optionally an antibacterial agent into the urethra.
Inventor(s):	Kock; Nils G. (S-413 19, Goteborg, SE), Lycke; Gerhard (S-421 67 Vastra Frolunda, SE)
Assignee:
Filing Date:	Jun 07, 1995
Application Number:	08/478,982
Claims:	1. A method of treating erectile dysfunction wherein a composition comprising a therapeutically effective amount of nitroglycerine and a hydrophilic vehicle is administered into the urethra. 2. A method according to claim 1, wherein said composition additionally comprises vasoactive intestinal polypeptide. 3. A method according to claim 1, wherein nitroglycerine is administered in an amount of at most 5 mg. 4. A method according to claim 1 wherein nitroglycerine is administered in an amount of 0.5-1.5 mg. 5. A method according to claim 1, wherein said composition is administered into the urethra in a volume of 1-6 ml. 6. A method according to claim 1, wherein said composition additionally comprises a prostaglandin. 7. A method according to claim 1, wherein said composition additionally comprises an .alpha.-receptor blocker. 8. A method according to claim 7, wherein said .alpha.-receptor blocker is selected from the group consisting of phentolamine, phenoxybenzamine and prazosine. 9. A method according to claim 1, wherein the active substance is administered by instillation. 10. A method according to claim 1 wherein said method additionally comprises administering an antibacterial agent into the urethra. 11. A method according to claim 6 wherein said prostaglandin is prostaglandin E.sub.1. 12. A method according to claim 6 wherein said prostaglandin is prostaglandin E.sub.2.