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Last Updated: March 29, 2024

Claims for Patent: 6,046,202


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Summary for Patent: 6,046,202
Title: Use of thiazolidinedione derivatives in the treatment of insulin resistance
Abstract:The present invention provides methods of using thiazolidinedione in the treatment of insulin resistance.
Inventor(s): Antonucci; Tammy (Thousand Oaks, CA), Lockwood; Dean (Ann Arbor, MI), Norris; Rebecca (Kewadin, MI)
Assignee: Warner-Lambert Company (Morris Plains, NJ)
Application Number:09/168,515
Patent Claims: 1. A method of treating a patient having insulin resistance characterized by hyperinsulinemia and failure to respond to exogenous insulin, the method comprising administering to the patient a therapeutically effective amount of (+)-5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl )methoxy]phenyl]methyl]-2,4-thiazolidinedione (Troglitazone).

2. A method of treating a patient having insulin resistance characterized by hyperinsulinemia and failure to respond to exogenous insulin, the method comprising administering to the patient a therapeutically effective amount of 5-[p-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione (Pioglitazone).

3. A method of treating a patient having insulin resistance characterized by hyperinsulinemia and failure to respond to exogenous insulin, the method comprising administering to the patient a therapeutically effective amount of 5-(4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl)-2,4-thiazolidinedione (Rosiglitazone).

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