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Last Updated: March 28, 2024

Details for Patent: 5,912,238


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Summary for Patent: 5,912,238
Title: Heteroatoms-containing tricyclic compounds
Abstract:The invention concerns the compounds of formula I ##STR1## wherein the substituents have various significances. They are prepared by several processes including epimerizing replacement, treatment with cyanogen bromide or thiophosgene, treatment with an acid having a non-nucleophilic anion, treatment with dimethylsulfoxide and acetic anhydride, acylation, treatment with an oxalyl derivative and ammonia, methylation, oxidation, deprotection and protection. They possess interesting pharmacological activity as antiinflammatory, immunosuppressant, antiproliferative and chemotherapeutic drug resistance reversing agents.
Inventor(s): Baumann; Karl (Vienna, AT), Emmer; Gerhard (Vienna, AT)
Assignee: Novartis AG (Basel, CH)
Application Number:08/276,276
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

Drugs Protected by US Patent 5,912,238

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 5,912,238

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany39 37 336Nov 09, 1989
Germany39 38 132Nov 16, 1989
Germany39 42 831Dec 23, 1989
Germany39 42 833Dec 23, 1989
Germany40 06 819Mar 05, 1990

International Family Members for US Patent 5,912,238

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 126803 ⤷  Try a Trial
Australia 640963 ⤷  Try a Trial
Australia 6584390 ⤷  Try a Trial
Canada 2029694 ⤷  Try a Trial
Germany 10299040 ⤷  Try a Trial
Germany 69021833 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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