Details for Patent: 8,003,353
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Which drugs does patent 8,003,353 protect, and when does it expire?
Patent 8,003,353 protects NASCOBAL and is included in one NDA.
Summary for Patent: 8,003,353
Title: | Cyanocobalamin low viscosity aqueous formulations for intranasal delivery |
Abstract: | A stable pharmaceutical mercury-free aqueous solution of cyanocobalamin comprised of cyanocobalamin and water wherein said solution of cyanocobalamin is suitable for intranasal administration, has a viscosity less than about 1000 cPs, and wherein said solution of cyanocobalamin has a bioavailability of cyanocobalamin when administered intranasally of at least about 7% relative to an intramuscular injection of cyanocobalamin with the proviso that the solution is essentially free of mercury and mercury-containing compounds. The present invention is also directed towards a method for elevating the vitamin B12 levels in the cerebral spinal fluid (CSF) comprising administering intranasally a sufficient amount of a mercury-free cyanocobalamin solution so as to increase the average ratio of vitamin B12 in the CSF to that in the blood serum (B12 CSF/B12 Serum.times.100) to at least about 1.1 comprising intranasally administering an aqueous solution of a cyanocobalamin, wherein said solution of cyanocobalamin has a bioavailability of at least 7% relative to an intramuscular injection of a cyanocobalamin. |
Inventor(s): | Quay; Steven C. (Edmonds, WA), Aprile; Peter C. (East Northport, NY), Go; Zenaida O. (Clifton, NJ), Sileno; Anthony P. (Brookhaven Hamlet, NY) |
Assignee: | Par Pharmaceutical, Inc. (Woodcliff Lake, NJ) |
Application Number: | 12/142,240 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 8,003,353 |
Patent Claim Types: see list of patent claims | Use; Formulation; |
Drugs Protected by US Patent 8,003,353
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endo Pharms Inc | NASCOBAL | cyanocobalamin | SPRAY, METERED;NASAL | 021642-001 | Jan 31, 2005 | AB | RX | Yes | Yes | ⤷ Try a Trial | ⤷ Try a Trial | NASAL ADMINISTRATION OF CYANOCOBALAMIN | ⤷ Try a Trial | |||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |