CLINICAL TRIALS PROFILE FOR TELAGLENASTAT
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Clinical Trials for Telaglenastat
Trial ID | Title | Status | Sponsor | Phase | Summary |
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NCT02771626 ↗ | Study CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC) | Completed | Calithera Biosciences, Inc | Phase 1/Phase 2 | This study is an open-label Phase 1/ 2 evaluation of CB-839 in combination with nivolumab in patients with clear cell renal cell carcinoma, melanoma, and non-small cell lung cancer. |
NCT03057600 ↗ | Study of CB-839 in Combination w/ Paclitaxel in Patients of African Ancestry and Non-African Ancestry With Advanced Triple Negative Breast Cancer (TNBC) | Completed | Calithera Biosciences, Inc | Phase 2 | CX-839-007 is an open-label Phase 2 study of the combination of CB-839 with paclitaxel in patients of African ancestry and non-African ancestry with advanced triple negative breast cancer. Multiple single-arm cohorts will be enrolled in which 800 mg twice daily (BID) CB-839 will be administered in combination with the full approved dose of paclitaxel. |
NCT03163667 ↗ | ENTRATA: CB-839 With Everolimus vs. Placebo With Everolimus in Patients With Renal Cell Carcinoma (RCC) | Completed | Calithera Biosciences, Inc | Phase 2 | Phase 2 Study Comparing CB-839 in Combination with Everolimus (CBE) vs. Placebo with Everolimus (PboE) in Patients with Advanced or Metastatic RCC |
NCT03428217 ↗ | CANTATA: CB-839 With Cabozantinib vs. Cabozantinib With Placebo in Patients With Metastatic Renal Cell Carcinoma | Completed | Calithera Biosciences, Inc | Phase 2 | This clinical trial is a randomized Phase 2 evaluation of CB-839 (telaglenastat) in combination with cabozantinib versus placebo with cabozantinib in patients with advanced or metastatic Renal Cell Carcinoma with a clear cell component. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Summary |
Clinical Trial Conditions for Telaglenastat
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Clinical Trial Locations for Telaglenastat
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Clinical Trial Progress for Telaglenastat
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Clinical Trial Sponsors for Telaglenastat
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