Centella Asiatica Selected Triterpenes (CAST) for Diabetic Neuropathy
Completed
National Center for Complementary and Integrative Health (NCCIH)
Phase 2
2007-09-01
The purpose of this protocol is to investigate the safety, tolerability and effectiveness of
CAST as a treatment for diabetic neuropathy. The primary outcome measure will be Total
Neuropathic Symptom Score. Secondary outcomes will be neurological disability score, nerve
conduction measurements and quantitative sensory testing. Statistical analyses will compare
changes from baseline for CAST- and placebo-treated groups at both time points, compare
effects of CAST at 6 and 12 months and, if numbers permit, compare doses.
Centella Asiatica Selected Triterpenes (CAST) for Diabetic Neuropathy
Completed
Oregon Health and Science University
Phase 2
2007-09-01
The purpose of this protocol is to investigate the safety, tolerability and effectiveness of
CAST as a treatment for diabetic neuropathy. The primary outcome measure will be Total
Neuropathic Symptom Score. Secondary outcomes will be neurological disability score, nerve
conduction measurements and quantitative sensory testing. Statistical analyses will compare
changes from baseline for CAST- and placebo-treated groups at both time points, compare
effects of CAST at 6 and 12 months and, if numbers permit, compare doses.
Effectiveness of Olive Oil Local Application in Orthodontic Patients.
Recruiting
Minia University
Phase 1
2020-01-01
The large body of evidence supports the chemotherapeutic potential of substances found in
Olive Oil (OO), acting on different sides, such as inflammation, oxidative damage, and even
epigenetic modulation. The consumption of OO should be suggested in a healthy diet instead of
other types of oils. It looks worthy, to determine the effect of local application of Olive
Oil in decreasing the friction between brackets and wires during orthodontic treatment.
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