Olmesartan and an add-on Treatment in Patients With Mild to Moderate Hypertension
Completed
Sankyo Pharma Gmbh
Phase 4
2006-03-01
This study is to assess the safety and efficacy of an add-on treatment algorithm with
olmesartan, hydrochlorothiazide and amlodipine in patients with mild to moderate
hypertension.
Safety and Efficacy Study of a Triple Combination Therapy in Subjects With Hypertension
Completed
Daiichi Sankyo Inc.
Phase 3
2008-05-01
To determine the effectiveness of four different strength combinations of three approved
anti-hypertension therapies (olmesartan medoxomil, amlodipine, and hydrochlorothiazide) for
lowering blood pressure.
Safety and Efficacy Study of a Triple Combination Therapy in Subjects With Hypertension
Completed
Daiichi Sankyo, Inc.
Phase 3
2008-05-01
To determine the effectiveness of four different strength combinations of three approved
anti-hypertension therapies (olmesartan medoxomil, amlodipine, and hydrochlorothiazide) for
lowering blood pressure.
A Dose Escalation Study of a Combination Antihypertensive Drug in the Treatment of Various Groups of Patients Who do Not Respond to Single Drug Treatment of Their High Blood Pressure
Completed
Integrium
Phase 4
2008-11-01
The initial 12 week portion of this 20 week study will examine the ability of a combination
of olmesartan medoxomil and amlodipine to lower the blood pressure of patients with high
blood pressure who have not had sufficient blood pressure reduction using one
anti-hypertension drug (monotherapy). The final 8 weeks of this 20 week study will examine
the ability of a combination of olmesartan medoxomil, amlodipine and hydrochlorothiazide to
lower blood pressure in the same patient population. All three medications being tested have
been approved by the FDA for the treatment of high blood pressure, but only amlodipine and
olmesartan are currently approved for use in combination form.
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