Efficacy Study of Folic Acid Supplementation in Adolescent Epileptics
Unknown status
Maharashtra University of Health Sciences
Phase 3
2015-03-01
The present study is planned to study effect of folic acid supplementation on homocysteine
levels and CV risk factors such as BP and lipids in adolescent epileptics taking
anti-epileptic drugs (AEDs).
Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate Monotherapy
Terminated
Jawaharlal Institute of Postgraduate Medical Education & Research
Phase 3
2016-09-01
RA (Rheuatoid arthritis) is a multisystem disease that mainly involves joints resulting in
destructive arthritis if not treated rapidly. Inspite of various advances in field of early
diagnosis and treatment of RA, there is still a need for better understanding of the efficacy
and safety of various combinations of conventional DMARDS, and to rank them in order
accordingly, so as to give a clearer vision for further management of RA once MTX monotherapy
fails, so as to achieve remission as soon as possible. The study will be conducted at the
Department of Clinical Immunology, JIPMER (Jawaharlal Institute of Postgraduate Medical
Education & Research). patients who fail methotrexate monotherapy will be randomised to 2
treatment arms - either a combination of Sulfasalazine (SSZ), Hydroxychloroquine (HCQ) and
Methotrexate (MTX) or Leflunomide (LEF), Hydroxychloroquine (HCQ) and Methotrexate (MTX)
Pemetrexed Maintenance in Patients With Urothelial Carcinoma Who Completed First Line Platinum-based Chemotherapy
Unknown status
Korean Cancer Study Group
Phase 3
2017-01-01
This study aims to verify superiority of pemetrexed maintenance to observation for patient
without disease progression after 1 st line cisplatin-based chemotherapy.
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