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Last Updated: June 2, 2024

CLINICAL TRIALS PROFILE FOR TEW-7197

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Clinical Trials for TEW-7197

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT02160106 ↗	First in Human Dose Escalation Study of Vactosertib (TEW-7197) in Subjects With Advanced Stage Solid Tumors	Completed	National OncoVenture	Phase 1	The phase I dose escalation study will investigate the safety, tolerability, and pharmacokinetics of the TGF-β pathway inhibitor TEW 7197 in subjects with advanced, refractory solid tumors.
NCT02160106 ↗	First in Human Dose Escalation Study of Vactosertib (TEW-7197) in Subjects With Advanced Stage Solid Tumors	Completed	MedPacto, Inc.	Phase 1	The phase I dose escalation study will investigate the safety, tolerability, and pharmacokinetics of the TGF-β pathway inhibitor TEW 7197 in subjects with advanced, refractory solid tumors.
NCT03074006 ↗	Dose Escalation and Proof-of-Concept Studies of Vactosertib (TEW-7197) Monotherapy in Patients With MDS	Completed	MedPacto, Inc.	Phase 1	This is a prospective, open-label, multicenter, phase 1/2 study of TEW-7197 in patients with low and intermediate risk of myelodysplastic syndrome (MDS).
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for TEW-7197

Condition Name

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Condition Name for
Intervention	Trials
Myelodysplastic Syndromes	2
Gastric Cancer	2
Metastatic Colorectal Cancer	1
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Condition MeSH

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Condition MeSH for
Intervention	Trials
Adenocarcinoma	4
Neoplasms	2
Multiple Myeloma	2
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Clinical Trial Locations for TEW-7197

Trials by Country

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Trials by Country for
Location	Trials
United States	10
Korea, Republic of	7
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Trials by US State

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Trials by US State for
Location	Trials
New York	3
Ohio	2
Tennessee	1
North Carolina	1
California	1
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Clinical Trial Progress for TEW-7197

Clinical Trial Phase

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Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 2	3
Phase 1/Phase 2	6
Phase 1	6
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Clinical Trial Status

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Clinical Trial Status for
Clinical Trial Phase	Trials
Not yet recruiting	5
Recruiting	4
Active, not recruiting	3
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Clinical Trial Sponsors for TEW-7197

Sponsor Name

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Sponsor Name for
Sponsor	Trials
MedPacto, Inc.	8
AstraZeneca	2
Samsung Medical Center	2
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Sponsor Type

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Sponsor Type for
Sponsor	Trials
Industry	11
Other	9
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